منابع مشابه
Postprandial Hyperlipidemia and Remnant Lipoproteins
Fasting hypertriglyceridemia is positively associated with the morbidity of coronary heart disease (CHD), and postprandial (non-fasting) hypertriglyceridemia is also correlated with the risk status for CHD, which is related to the increase in chylomicron (CM) remnant lipoproteins produced from the intestine. CM remnant particles, as well as oxidized low density lipoprotein (LDL) or very low den...
متن کاملRemnant lipoproteins: measurement and clinical significance.
In this issue of the Journal, Chan et al. (1 ) make the significant observation, by three distinct measures, that the concentrations of remnant lipoproteins (RLPs) in plasma are increased in patients with obesity. This increase in RLPs could explain, in part, the increased cardiovascular risk associated with obesity (2 ). To date, although LDLand HDL-cholesterol are clearly accepted as independ...
متن کاملRemnant lipoproteins inhibit malaria sporozoite invasion of hepatocytes
Remnants of lipoproteins, intestinal chylomicrons, and very low density lipoprotein (VLDL), are rapidly cleared from plasma and enter hepatocytes. It has been suggested that remnant lipoproteins are initially captured in the space of Disse by heparan sulfate proteoglycans (HSPGs), and that their subsequent internalization into hepatocytes is mediated by members of the LDL-receptor gene family. ...
متن کاملHepatic catabolism of remnant lipoproteins: where the action is.
Brown and Goldstein described the classical pathway of low-density lipoprotein (LDL) catabolism in human fibroblasts, initiated by LDL-binding to the LDL receptor (LDLR) and followed by endocytosis and lysosomal catabolism of its components.1 The initial steps in the hepatic catabolism of chylomicron remnants and large very-low-density lipoprotein (VLDL) remnants have turned out to be more comp...
متن کاملRemnant Lipoproteins Induce Proatherothrombogenic Molecules in Endothelial Cells
Hideki Doi, Kiyotaka Kugiyama, Hideki Oka, Seigo Sugiyama, Nobuhiko Ogata, Shun-ichi Through a Redox-Sensitive Mechanism Remnant Lipoproteins Induce Proatherothrombogenic Molecules in Endothelial Cells Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2000 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas...
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ژورنال
عنوان ژورنال: Current Opinion in Lipidology
سال: 2020
ISSN: 0957-9672
DOI: 10.1097/mol.0000000000000682